Confocal Time-of-flight Diffuse Optical Tomography Diffuse Optical Tomography Light scattering by tissue severely limits how deep beneath the surface one can image, and the spatial resolution one can obtain from these images. Diffuse optical tomography (DOT) is one of...
DeepDOF Intra-operative histopathology Microscopic evaluation of resected tissue plays a central role in the surgical management of cancer. Because optical microscopes have a limited depth-of-field (DOF), resected tissue is either frozen or preserved with chemical...
Differential Digital Confocal Aperture Why Line-scanning Confocal Imaging? Probe-based fluorescence microendoscopy has demonstrated great potential to improve early cancer detection. When imaging thick, highly scattering biological tissue, the high level of scattering...
Confocal microendoscope Cervical cancer incidence and mortality rates remain high in medically underserved areas. In this study, we present a low-cost (<$5,000), portable and user-friendly confocal microendoscope, and we report on its clinical use to image...
